Photon Scattering Signal Amplification in Gold-Viral Particle Ligation Towards Fast Infection Screening

The polarization states of scattered photons can be used to map or image the anisotropic features a nanostructure. However, scattering strength depends heavily on refractivity contrast in near field under measurement, which limits imaging sensitivity for viral particles have little with their nano-ambientes. In this paper, we show photon signal magnified by introducing more abrupt change at virus particle using antibody-conjugated gold nanoparticles (AuNPs), allowing presence such viruses detected. Using two different deep learning methods minimize noise, AuNPs ligated is enhanced significantly compared that bare particle. This confirmed Finite Difference Time Domain (FDTD) numerical simulations. state spectra from virus-gold doublet 5.4 times higher than conventional microscope image.